Products
PAK2 antibody
- Product Name
- PAK2 antibody
- Catalogue No.
- FNab06122
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- p21 protein (Cdc42/Rac)-activated kinase 2
- Alternative Names
- Serine/threonine-protein kinase PAK 2|Gamma-PAK|PAK65|S6/H4 kinase|p21-activated kinase 2 (PAK-2)|p58|PAK-2p27 (p27)|PAK-2p34 (p34) Alternative names: C-t-PAK2|PAK2 antibody
- UniProt ID
- Q13177
- Observed MW
- 58 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab06122(PAK2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse kidney using FNab06122(PAK2 antibody) at dilution of 1:100
Immunofluorescence analysis of A549 cells using FNab06122(PAK2 antibody). Blue: DAPI for nuclear staining.
- Background
- The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
