Products
OCLN antibody
- Product Name
- OCLN antibody
- Catalogue No.
- FNab05957
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- occludin
- Alternative Names
- Occludin|OCLN antibody
- UniProt ID
- Q16625
- Observed MW
- 59 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20-1:200
Validated Images
HUVEC cells were subjected to SDS PAGE followed by western blot with FNab05957 (Occludin antibody) at dilution of 1:1500
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab05957( Occludin Antibody) at dilution of 1:500
Immunofluorescent analysis of MCF7 cells, using antibody FNab05957 at 1:50 dilution.
- Background
- This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
