Products
NLRX1 antibody
- Product Name
- NLRX1 antibody
- Catalogue No.
- FNab05759
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- NLR family member X1
- Alternative Names
- Caterpiller protein 11.3 antibody, CLR11.3 antibody, DLNB26 antibody, NLR family member X1 antibody, NLRX1 antibody, NOD26 antibody, NOD5 antibody, NOD9 antibody
- UniProt ID
- Q86UT6
- Observed MW
- 110 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:10-1:100
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab05759(NLRX1 antibody) at dilution of 1:1000
IP Result of anti-NLRX1 (IP:FNab05759, 3ug; Detection:FNab05759 1:800) with mouse heart tissue lysate 3520ug.
Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab05759(NLRX1 Antibody) at dilution of 1:200
Immunofluorescent analysis of HepG2 cells, using FNab05759(NLRX1 Antibody) at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Background
- Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH(RIG-like helicase)-MAVS interaction(PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species(PubMed:18219313).
