Products
MUC1 antibody
- Product Name
- MUC1 antibody
- Catalogue No.
- FNab05427
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- mucin 1, cell surface associated
- Alternative Names
- CA15 3 antibody, CA153 antibody, CA15-3 antibody, Carcinoma associated mucin antibody, CD227 antibody, EMA antibody, Episialin antibody, H23AG antibody, KL-6 antibody, MAM6 antibody, MUC 1 antibody, MUC1 antibody, MUC1 beta antibody, MUC1 CT antibody, MUC1 NT antibody, Mucin 1 antibody, Peanut reactive urinary mucin antibody, PEM antibody, PEMT antibody, Polymorphic epithelial mucin antibody, PUM antibody, Tumor associated mucin antibody
- UniProt ID
- P15941
- Observed MW
- 122 kDa、23-30 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:20-1:200
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab05427(CA15-3,MUC1 antibody) at dilution of 1:1500
Immunohistochemistry of paraffin-embedded human lung cancer using FNab05427(CA15-3,MUC1 antibody) at dilution of 1:50
- Background
- The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
