Products
MCL1 antibody
- Product Name
- MCL1 antibody
- Catalogue No.
- FNab05052
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- myeloid cell leukemia sequence 1 (BCL2-related)
- Alternative Names
- Induced myeloid leukemia cell differentiation protein Mcl-1|Bcl-2-like protein 3 (Bcl2-L-3)|Bcl-2-related protein EAT/mcl1|mcl1/EAT|MCL1|BCL2L3 antibody
- UniProt ID
- Q07820
- Observed MW
- 37 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:100 - 1:200
Validated Images
Raji cells were subjected to SDS PAGE followed by western blot with FNab05052(MCL1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using FNab05052( MCL1 Antibody) at dilution of 1:100
- Background
- This gene encodes an anti- apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
