Products
MAP1B antibody
- Product Name
- MAP1B antibody
- Catalogue No.
- FNab04974
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- microtubule-associated protein 1B
- Alternative Names
- Microtubule-associated protein 1B (MAP-1B)|MAP1B heavy chain|MAP1 light chain LC1|MAP1B antibody
- UniProt ID
- P46821
- Observed MW
- 320 kDa
Application
- Tested Applications
- ELISA, WB, IHC, FC, IF
- Recommended dilution
- WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with FNab04974(MAP1B antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab04974(MAP1B Antibody) at dilution of 1:50
Immunofluorescent analysis of SH-SY5Y cells using FNab04974 ( MAP1B Antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)
- Background
- Facilitates tyrosination of alpha-tubulin in neuronal microtubules(By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.
