Products
KPNA1 antibody
- Product Name
- KPNA1 antibody
- Catalogue No.
- FNab04634
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- karyopherin alpha 1 (importin alpha 5)
- Alternative Names
- Importin subunit alpha-5|Karyopherin subunit alpha-1|Nucleoprotein interactor 1 (NPI-1)|RAG cohort protein 2|SRP1-beta|Importin subunit alpha-5 antibody, N-terminally processed|KPNA1|RCH2 antibody
- UniProt ID
- P52294
- Observed MW
- 66 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab04634(KPNA1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using FNab04634(KPNA1 antibody) at dilution of 1:50
Immunofluorescence analysis of U2OS cells using FNab04634(KPNA1 antibody) at dilution of 1:100
- Background
- The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.
