Insulin antibody

Synonyms:ILPR antibody, INS antibody, insulin antibody, IRDN antibody
Catalogue No.:FNab04339Reactivity:Human, Mouse
Host:MouseTested Application:ELISA, IHC
Clonality:monoclonalIsotype:IgG2a
  • SPECIFICATIONS
Product Name
Insulin antibody
Catalogue No.
FNab04339
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG2a
Clone ID
0H2
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
insulin
Alternative Names
ILPR antibody, INS antibody, insulin antibody, IRDN antibody
UniProt ID
P01308
Application
Tested Applications
ELISA, IHC
Recommended dilution
IHC: 1:500-1:5000
Validated Images
Immunohistochemistry of paraffin-embedded human pancreas tissue slide using FNab04339(Insulin Antibody) at dilution of 1:5000
Background
Insulin is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A-and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in insulin results in type 1 diabetes mellitus. Insulin may also exist 36 kDa form corresponding to the hexameric insulin form.