Products
IL6R antibody
- Product Name
- IL6R antibody
- Catalogue No.
- FNab04284
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- interleukin 6 receptor
- Alternative Names
- CD126 antibody, gp80 antibody, IL 6 receptor subunit alpha antibody, IL 6R 1 antibody, IL 6R alpha antibody, IL 6R subunit alpha antibody, IL 6RA antibody, IL-6 R alpha antibody, IL-6R antibody, IL6RA antibody, interleukin 6 receptor antibody, Membrane glycoprotein 80 antibody
- UniProt ID
- P08887
- Observed MW
- 80 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:50-1:200; IP: 1:500-1:1000
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab04284 (IL6R antibody) at dilution of 1:800
IP Result of anti-IL6-R (IP:FNab04284, 4ug; Detection:FNab04284 1:500) with mouse spleen tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human spleen tissue slide using FNab04284(IL-6R antibody) at dilution of 1:200
- Background
- Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity.
