Products
NFKBIB antibody
- Product Name
- NFKBIB antibody
- Catalogue No.
- FNab04199
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
- Alternative Names
- NF-kappa-B inhibitor beta (NF-kappa-BIB)|I-kappa-B-beta (IkB-B antibody, IkB-beta antibody, IkappaBbeta)|Thyroid receptor-interacting protein 9 (TR-interacting protein 9 antibody, TRIP-9)|NFKBIB|IKBB|TRIP9 antibody
- UniProt ID
- Q15653
- Observed MW
- 40 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab04199(NFKBIB antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer using FNab04199(NFKBIB antibody) at dilution of 1:100
Immunofluorescence analysis of U2OS cells using FNab04199(NFKBIB antibody). Blue: DAPI for nuclear staining.
- Background
- The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
