RNF40 antibody

Synonyms:E3 ubiquitin-protein ligase BRE1B (BRE1-B)|95 kDa retinoblastoma-associated protein (RBP95)|RING finger protein 40|RING-type E3 ubiquitin transferase BRE1B|RNF40|BRE1B|KIAA0661 antibody
Catalogue No.:FNab07358Reactivity:Human
Host:RabbitTested Application:ELISA, WB, IHC, IF,IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
RNF40 antibody
Catalogue No.
FNab07358
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
ring finger protein 40
Alternative Names
E3 ubiquitin-protein ligase BRE1B (BRE1-B)|95 kDa retinoblastoma-associated protein (RBP95)|RING finger protein 40|RING-type E3 ubiquitin transferase BRE1B|RNF40|BRE1B|KIAA0661 antibody
UniProt ID
O75150
Observed MW
140 kDa
Application
Tested Applications
ELISA, WB, IHC, IF,IP
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:100; ChIP : 1:50 - 1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab07358(RNF40 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human testis using FNab07358(RNF40 antibody) at dilution of 1:50
Immunofluorescence analysis of MCF-7 cells using FNab07358( RNF40 Antibody) at dilution of 1:50
Background
The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.