Products
IGF2BP3 antibody
- Product Name
- IGF2BP3 antibody
- Catalogue No.
- FNab04173
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- insulin-like growth factor 2 mRNA binding protein 3
- Alternative Names
- Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3 antibody, IMP-3)|IGF-II mRNA-binding protein 3|KH domain-containing protein overexpressed in cancer (hKOC)|VICKZ family member 3|IGF2BP3|IMP3|KOC1|VICKZ3 antibody
- UniProt ID
- O00425
- Observed MW
- 72 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04173(IGF2BP3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver using FNab04173(IGF2BP3 antibody) at dilution of 1:100
- Background
- The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
