HMOX1 antibody

Synonyms:Heme oxygenase 1 antibody, HMOX1 antibody, HO antibody, HO 1 antibody, HO1 antibody, HSP32 antibody
Catalogue No.:FNab03937Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IP, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
HMOX1 antibody
Catalogue No.
FNab03937
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
heme oxygenase(decycling) 1
Alternative Names
Heme oxygenase 1 antibody, HMOX1 antibody, HO antibody, HO 1 antibody, HO1 antibody, HSP32 antibody
UniProt ID
P09601
Observed MW
33 kDa
Application
Tested Applications
ELISA, WB, IHC, IP, IF
Recommended dilution
WB: 1:500-1:1000; IP: 1:500-1:2000; IHC: 1:100-1:400; IF: 1:20-1:200
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab03937(HMOX1 antibody) at dilution of 1:600
IP Result of anti-HMOX1 (IP:FNab03937, 3ug; Detection:FNab03937 1:1000) with HeLa cells lysate 3000ug.
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab03937(HO-1 Antibody) at dilution of 1:200
Immunofluorescent analysis of ( -20℃ Ethanol ) fixed HT-1080 cells using FNab03937 (HO-1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
Background
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.