HeLa cells were subjected to SDS PAGE followed by western blot with FNab03808(HDGF antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney using FNab03808(HDGF antibody) at dilution of 1:100
Background
This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.