Products
TBP antibody
- Product Name
- TBP antibody
- Catalogue No.
- FNab08527
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG2a
- Clone ID
- 7B0
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- TATA box binding protein
- Alternative Names
- GTF2D antibody, GTF2D1 antibody, SCA17 antibody, TATA binding factor antibody, TATA box binding protein antibody, TATA box factor antibody, TATA sequence binding protein antibody, TBP antibody, TF2D antibody, TFIID antibody
- UniProt ID
- P20226
- Observed MW
- 38 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:2000-1:5000; IP: 1:500-1:1000
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab08527(TBP antibody) at dilution of 1:4000
IP Result of anti-TBP (IP:FNab08527, 3ug; Detection:FNab08527 1:800) with HEK-293 cells lysate 1800ug.
- Background
- General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex(PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC(preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
