Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab03090( FGF13 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse kidney using FNab03090( FGF13 Antibody) at dilution of 1:50
Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini.