anti- Cyclophilin A antibody

FNab02134 Catalogue No.

Synonyms: Cyclophilin A, Cyclosporin A binding protein, CYPA, CYPH, PPIA, PPIase A, Rotamase A
Host: Rabbit
Reactivity: Human, Mouse, Rat
Isotype: IgG
Tested Application: ELISA, WB, IHC, IF, FC

Manual

Product Information

Product Name: anti- Cyclophilin A antibody
Catalogue No.: FNab02134
Size: 100µg
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

: This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported.

Immunogen Information

Immunogen: peptidylprolyl isomerase A (cyclophilin A)
Synonyms: Cyclophilin A, Cyclosporin A binding protein, CYPA, CYPH, PPIA, PPIase A, Rotamase A
Observed MW: 18 kDa

Application

Uniprot information

Images

Image 1: Immunohistochemistry of paraffin-embedded human colon cancer using FNab02134 (CYPA antibody) at dilution of 1:200
Image 2: Immunofluorescent analysis of HepG2 cells, using PPIA antibody FNab02134 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Image 4: K-562 cells were subjected to SDS PAGE followed by western blot with FNab02134 (CYPA antibody) at dilution of 1:1500

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