Products

CX3CR1 antibody

Synonyms:CMKBRL1 antibody, GPR13 antibody
Catalogue No.:FNab02090Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, FC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
CX3CR1 antibody
Catalogue No.
FNab02090
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
chemokine(C-X3-C motif) receptor 1
Alternative Names
CMKBRL1 antibody, GPR13 antibody
UniProt ID
P49238
Observed MW
47 kDa
Application
Tested Applications
ELISA, WB, IHC, FC
Recommended dilution
WB: 1:500-1:1000; IHC: 1:20-1:200
Validated Images
HL-60 cells were subjected to SDS PAGE followed by western blot with FNab02090(CX3CR1 antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human tonsillitis using FNab02090(CX3CR1 antibody) at dilution of 1:50
Background
Receptor for the CX3C chemokine fractalkine(CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions(PubMed:9390561, PubMed:23125415). Acts as coreceptor with CD4 for HIV-1 virus envelope protein(in vitro)(PubMed:9726990). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1(PubMed:14607932).