Products
ADGRE5 antibody
- Product Name
- ADGRE5 antibody
- Catalogue No.
- FNab01510
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- CD97 molecule
- Alternative Names
- Adhesion G protein-coupled receptor E5|Leukocyte antigen CD97|Adhesion G protein-coupled receptor E5 subunit alpha|Adhesion G protein-coupled receptor E5 subunit beta|ADGRE5|CD97 antibody
- UniProt ID
- P48960
- Observed MW
- 105 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200 - 1:2000; IHC: 1:50 - 1:100
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab01510(CD97 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab01510(CD97 antibody) at dilution of 1:100
- Background
- This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.
