Products
CD86 antibody
- Product Name
- CD86 antibody
- Catalogue No.
- FNab01504
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- CD86 molecule
- Alternative Names
- Activation B7 2 antigen antibody, B7 2 antibody, B70 antibody, BU63 antibody, CD28LG2 antibody, CD86 antibody, CD86 molecule antibody, CTLA 4 counter receptor B7.2 antibody, FUN 1 antibody, LAB72 antibody
- UniProt ID
- P42081
- Observed MW
- 75 kDa
Application
- Tested Applications
- ELISA, WB,IHC,IF
- Recommended dilution
- WB: 1:200-1:2000; IHC: 1:50-1:500; IF: 1:20-1:200
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01504(CD86 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01504(CD86 Antibody) at dilution of 1:200. heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Immunofluorescent analysis of RAW264.7 cells using FNab01504 ( CD86 Antibody) at dilution of 1:50.
- Background
- Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.(Microbial infection) Acts as a receptor for adenovirus subgroup B.
