Products
CD14 antibody
- Product Name
- CD14 antibody
- Catalogue No.
- FNab01426
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- CD14 molecule
- Alternative Names
- CD14 antibody, CD14 molecule antibody
- UniProt ID
- P08571
- Observed MW
- 50-55 kDa
Application
- Tested Applications
- ELISA, IHC, WB, IF, FC
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:100-1:400; IF: 1:50-1:500
Validated Images
HL-60 cells were subjected to SDS PAGE followed by western blot with FNab01426(CD14 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab01426(CD14 Antibody) at dilution of 1:200
Immunofluorescent analysis of ( -20℃ Ethanol ) fixed RAW 264.7 cells using FNab01426 (CD14 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- Coreceptor for bacterial lipopolysaccharide(PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide(LPS)(PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response(PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway(PubMed:16880211).
