Products
BMPR1A antibody
- Product Name
- BMPR1A antibody
- Catalogue No.
- FNab00922
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- bone morphogenetic protein receptor, type IA
- Alternative Names
- 10q23del antibody, Activin receptor like kinase 3 antibody, ACVRLK3 antibody, ALK 3 antibody, ALK3 antibody, BMP type 1A receptor antibody, BMPR 1A antibody, BMPR1A antibody, CD292 antibody, SKR5 antibody
- UniProt ID
- P36894
- Observed MW
- 60 kDa
Application
- Tested Applications
- ELISA, WB, IF, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00922(BMPR1A Antibody) at dilution of 1:1000
IP Result of anti-BMPR1A (IP:FNab00922, 4ug; Detection:FNab00922 1:500) with HEK-293 cells lysate 2000ug.
Immunofluorescent analysis of HeLa cells using FNab00922 (BMPR1A antibody) at dilution of 1:25 and Alexa Fluor 594-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
