Products
ORAI1 antibody
- Product Name
- ORAI1 antibody
- Catalogue No.
- FNab06001
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ORAI calcium release-activated calcium modulator 1
- Alternative Names
- CRACM1 antibody, FLJ14466 antibody, ORAI1 antibody, ORAI1 L1 antibody, ORAI1 L2 antibody, Orail L2 antibody, ORAT1 antibody, Protein orai 1 antibody, TMEM142A antibody, Transmembrane protein 142A antibody
- UniProt ID
- Q96D31
- Observed MW
- 45 kDa
Application
- Tested Applications
- ELISA, WB, IF
- Recommended dilution
- WB: 1:500-1:1000; IF: 1:10-1:100
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab06001(ORAI1 antibody) at dilution of 1:800
Immunofluorescent analysis of HEK-293 cells using FNab06001 (ORAI1 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- Ca(2+) release-activated Ca(2+)(CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1 . CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT(PubMed:16582901).
