Products
BAG1 antibody
- Product Name
- BAG1 antibody
- Catalogue No.
- FNab00786
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- BCL2-associated athanogene
- Alternative Names
- BAG family molecular chaperone regulator 1 (BAG-1)|Bcl-2-associated athanogene 1|BAG1|HAP antibody
- UniProt ID
- Q99933
- Observed MW
- 43 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab00786(BAG1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human esophagus using FNab00786(BAG1 antibody) at dilution of 1:50
- Background
- The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti- apoptotic effects of BCL2 and represents a link between growth factor receptors and anti- apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
