Products

Aurora B antibody

Synonyms:AIK2 antibody, AIM 1 antibody, AIM1 antibody, ARK 2 antibody, ARK2 antibody, AurB antibody, AURKB antibody, Aurora B antibody, aurora kinase B antibody, Aurora related kinase 2 antibody, Aurora/IPL1 related kinase 2 antibody, IPL1 antibody, STK 1 antibody, STK12 antibody, STK5 antibody
Catalogue No.:FNab00747Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Aurora B antibody
Catalogue No.
FNab00747
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
aurora kinase B
Alternative Names
AIK2 antibody, AIM 1 antibody, AIM1 antibody, ARK 2 antibody, ARK2 antibody, AurB antibody, AURKB antibody, Aurora B antibody, aurora kinase B antibody, Aurora related kinase 2 antibody, Aurora/IPL1 related kinase 2 antibody, IPL1 antibody, STK 1 antibody, STK12 antibody, STK5 antibody
UniProt ID
Q96GD4
Observed MW
16kd, 35-45kd
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:200-1:2000; IHC: 1:20-1:200
Validated Images
Mouse liver were subjected to SDS PAGE followed by western blot with FNab00747(Aurora B Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon tissue slide using FNab00747(Aurora B Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Background
Aurora B(AURKB) is also named as aurora kinase B, AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5 and belongs to the Aurora subfamily. Aurora kinase B is a chromosomal passenger serine/threonine protein kinase that regulates accurate chromosomal segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachments, and regulation of the mitotic checkpoint(PMID:18311747). Expression levels of AURKB are increased in the anaplastic thyroid carcinoma cell lines ARO, Cal 62, and KAT-4(PMID:15562011).