Products

Angiotensinogen antibody

Synonyms:AGT antibody, Ang I Angiotensin 2 antibody, Ang II Angiotensin 3 antibody, Ang III antibody, Angiotensin I antibody, Angiotensin II antibody, Angiotensin III antibody, Angiotensinogen antibody, ANHU antibody, Des Asp[1] angiotensin II antibody, FLJ92595 antibody, FLJ97926 antibody, Serpin A8 antibody, SERPINA8 antibody
Catalogue No.:FNab00394Reativity:Human
Host:RabbitTested Application:ELISA, WB, IF, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Angiotensinogen antibody
Catalogue No.
FNab00394
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
angiotensinogen(serpin peptidase inhibitor, clade A, member 8)
Alternative Names
AGT antibody, Ang I Angiotensin 2 antibody, Ang II Angiotensin 3 antibody, Ang III antibody, Angiotensin I antibody, Angiotensin II antibody, Angiotensin III antibody, Angiotensinogen antibody, ANHU antibody, Des Asp[1] angiotensin II antibody, FLJ92595 antibody, FLJ97926 antibody, Serpin A8 antibody, SERPINA8 antibody
UniProt ID
P01019
Observed MW
53 kDa
Application
Tested Applications
ELISA, WB, IF, IHC
Recommended dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
human plasma tissue were subjected to SDS PAGE followed by western blot with FNab00394(AGT antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human hepatocirrhosis tissue slide using FNab00394(AGT Antibody) at dilution of 1:50
Background
Angiotensinogen is a precursor of angiotensin II(Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme(ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.