K562 cell lysates were subjected to SDS PAGE followed by western blot with FNab10716(IRF2BP2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab10716(IRF2BP2 antibody) at dilution of 1:100
Background
Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscle.