Raji cells were subjected to SDS PAGE followed by western blot with FNab10510(L-Selectin antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human gastric cancer slide using FNab10510(L-Selectin antibody) at dilution of 1:50
Immunofluorescent analysis of NIH/3T3 cells using FNab10510(L-Selectin antibody) at dilution of 1:50.
Background
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.