L-Selectin antibody

Synonyms:SELL antibody, CD62L antibody, LAM1 antibody, LECAM1 antibody, LEU8 antibody, LNHR antibody
Catalogue No.:FNab10510Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
L-Selectin antibody
Catalogue No.
FNab10510
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
L-selectin
Alternative Names
SELL antibody, CD62L antibody, LAM1 antibody, LECAM1 antibody, LEU8 antibody, LNHR antibody
UniProt ID
P14151
Observed MW
74 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
Validated Images
Raji cells were subjected to SDS PAGE followed by western blot with FNab10510(L-Selectin antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human gastric cancer slide using FNab10510(L-Selectin antibody) at dilution of 1:50
Immunofluorescent analysis of NIH/3T3 cells using FNab10510(L-Selectin antibody) at dilution of 1:50.
Background
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.