Products
DSG1 antibody
- Product Name
- DSG1 antibody
- Catalogue No.
- FNab10507
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Desmoglein-1
- Alternative Names
- DSG1 antibody, CDHF4 antibody, DG1 antibody, DSG antibody
- UniProt ID
- Q02413
- Observed MW
- 150 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab10507(DSG1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human trachea slide using FNab10507(DSG1 antibody) at dilution of 1:50
- Background
- This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.
