Phospho-Camk2a (T286) antibody

Synonyms:CaM kinase II subunit alpha antibody, CaMK II subunit alpha antibody, CAMK2 antibody, CAMK2A antibody, CAMK2B antibody, CAMK2D antibody, CAMK2G antibody, CAMKA antibody, CaMKII alpha antibody, KIAA0968 antibody
Catalogue No.:FNab10481Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Phospho-Camk2a (T286) antibody
Catalogue No.
FNab10481
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
calcium/calmodulin-dependent protein kinase II alpha
Alternative Names
CaM kinase II subunit alpha antibody, CaMK II subunit alpha antibody, CAMK2 antibody, CAMK2A antibody, CAMK2B antibody, CAMK2D antibody, CAMK2G antibody, CAMKA antibody, CaMKII alpha antibody, KIAA0968 antibody
UniProt ID
Q9UQM7
Observed MW
54 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab10481(Phospho-Camk2a-T286 antibody) at dilution of 1:1000
Background
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.