Products

COX2 antibody

Synonyms:COX 2 antibody, COX2 antibody, Cyclooxygenase 2 antibody, GRIPGHS antibody, hCox 2 antibody, PGG/HS antibody, PGH synthase 2 antibody, PGHS 2 antibody, PHS 2 antibody, PHS II antibody, Prostaglandin G/H synthase 2 antibody, Prostaglandin H2 synthase 2 antibody, PTGS2 antibody
Catalogue No.:FNab10407Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
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Product Name
COX2 antibody
Catalogue No.
FNab10407
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
prostaglandin-endoperoxide synthase 2(prostaglandin G/H synthase and cyclooxygenase)
Alternative Names
COX 2 antibody, COX2 antibody, Cyclooxygenase 2 antibody, GRIPGHS antibody, hCox 2 antibody, PGG/HS antibody, PGH synthase 2 antibody, PGHS 2 antibody, PHS 2 antibody, PHS II antibody, Prostaglandin G/H synthase 2 antibody, Prostaglandin H2 synthase 2 antibody, PTGS2 antibody
UniProt ID
P35354
Observed MW
50 kDa, 80 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
Various lysates were subjected to SDS PAGE followed by western blot with FNab10407(PTGS2 antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human liver using FNab10407(cox2 antibody) at dilution of 1:100
Background
COX2 (Prostaglandin G/H synthase 2; PTGS2) mediates the formation of prostaglandins from arachidonate. Its subunit structure is homodimer. The fully N-glycosylated PTGS2 is 72–74 kDa and the aglycosylated is 66 kDa(PMID:19656660 ). It also expresses a band of 39 kDa after unspecific cleavage(PMID:17509125 ). The 50 kDa band of fragmented PTGS2 has also previously been detected in AD brains(PMID:14724276 ).