Products
SYUB antibody
- Product Name
- SYUB antibody
- Catalogue No.
- FNab10048
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- synuclein, beta
- Alternative Names
- Beta synuclein antibody, SNCB antibody, synuclein antibody, beta antibody, SYUB antibody
- UniProt ID
- Q16143
- Observed MW
- 14-18 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:500
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab10048(SYUB antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab10048( SYUB Antibody) at dilution of 1:200
- Background
- Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine(6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
