Products
XPG antibody
- Product Name
- XPG antibody
- Catalogue No.
- FNab09547
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- excision repair cross-complementing rodent repair deficiency, complementation group 5
- Alternative Names
- COFS3 antibody, ERCC5 antibody, ERCM2 antibody, UVDR antibody, XPG antibody, XPGC antibody
- UniProt ID
- P28715?
- Observed MW
- 200 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:200-1:2000; IF: 1:20-1:200; IP: 1:200-1:2000
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09547(ERCC5 antibody) at dilution of 1:500
IP Result of anti-XPG (IP:FNab09547, 4ug; Detection:FNab09547 1:500) with HeLa cells lysate 1200ug.
- Background
- The human genes correcting DNA repair defects are termed excision-repair cross-complementing or ERCC genes. The ERCC5 gene corrects the excision repair deficiency of Chinese hamster ovary cell line UV135 of complementation group 5. The human ERCC5 gene product is a structure-specific endonuclease required for making the 3-prime incision during DNA nucleotide excision-repair(NER). It also plays an important role in regulating DNA excision repair, removal of bulky lesions caused by environmental chemicals or UV light [PMID:22815677].
