human kidney tissue were subjected to SDS PAGE followed by western blot with FNab04172(IGF2BP2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse liver using FNab04172(IGF2BP2 antibody) at dilution of 1:50
Background
This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes.