Products
WRAP53 antibody
- Product Name
- WRAP53 antibody
- Catalogue No.
- FNab09523
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- WD repeat containing, antisense to TP53
- Alternative Names
- FLJ10385 antibody, TCAB1 antibody, WDR79 antibody, WRAP53 antibody
- UniProt ID
- Q9BUR4
- Observed MW
- 72 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:200-1:1000
Validated Images
human kidney tissue were subjected to SDS PAGE followed by western blot with FNab09523(WRAP53 antibody) at dilution of 1:300
IP Result of anti-WRAP53 (IP:FNab09523, 4ug; Detection:FNab09523 1:300) with HeLa cells lysate 2480ug.
Immunohistochemistry of paraffin-embedded human testis using FNab09523(WRAP53 antibody) at dilution of 1:100
- Background
- Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs(scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level; it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.
