Products
USP21 antibody
- Product Name
- USP21 antibody
- Catalogue No.
- FNab09318
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ubiquitin specific peptidase 21
- Alternative Names
- Ubiquitin carboxyl-terminal hydrolase 21|Deubiquitinating enzyme 21|Ubiquitin thioesterase 21|Ubiquitin-specific-processing protease 21|USP21|USP23 antibody
- UniProt ID
- Q9UK80
- Observed MW
- 63 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200-1:2000; IHC: 1:20-1:200
Validated Images
RAW 264.7 cells were subjected to SDS PAGE followed by western blot with FNab09318(USP21 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab09318(USP21 Antibody) at dilution of 1:50
- Background
- Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di-and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination(By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates(PubMed:10799498). Deubiquitinates BAZ2A/TIP5 leading to its stabilization(PubMed:26100909).
