Products
USP1 antibody
- Product Name
- USP1 antibody
- Catalogue No.
- FNab09303
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 8F7
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ubiquitin specific peptidase 1
- Alternative Names
- Deubiquitinating enzyme 1 antibody, hUBP antibody, ubiquitin specific peptidase 1 antibody, Ubiquitin thiolesterase 1 antibody, UBP antibody, USP1 antibody
- UniProt ID
- O94782
- Observed MW
- 90 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:1000-1:10000; IHC: 1:20-1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09303(USP1 Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human cervical cancer using FNab09303(USP1 antibody) at dilution of 1:50
- Background
- Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).
