Products
UBE2C antibody
- Product Name
- UBE2C antibody
- Catalogue No.
- FNab09166
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 7E3
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ubiquitin-conjugating enzyme E2C
- Alternative Names
- DJ447F3.2 antibody, UBCH10 antibody, UBE2C antibody, Ubiquitin carrier protein C antibody, Ubiquitin protein ligase C antibody
- UniProt ID
- O00762
- Observed MW
- 17 kDa
Application
- Tested Applications
- ELISA, IF, IHC, WB
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab09166(UBE2C Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human colon cancer slide using FNab09166(UBE2C Antibody) at dilution of 1:50
- Background
- Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome(APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
