Products
TRPC4AP antibody
- Product Name
- TRPC4AP antibody
- Catalogue No.
- FNab09017
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 1C0
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- transient receptor potential cation channel, subfamily C, member 4 associated protein
- Alternative Names
- C20orf188 antibody, Protein TAP1 antibody, Protein TRUSS antibody, Trp4 associated protein antibody, Trpc4 associated protein antibody, TRPC4AP antibody, TRRP4AP antibody, TRUSS antibody
- UniProt ID
- Q8TEL6
- Observed MW
- 91 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:20-1:200
Validated Images
human heart tissue were subjected to SDS PAGE followed by western blot with FNab09017(TRPC4AP antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human breast cancer slide using FNab09017(TRPC4AP Antibody) at dilution of 1:50
- Background
- Substrate-specific adapter of a DCX(DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
