Products

anti- Tie2 antibody

FNab08690 Catalogue No.
Synonyms
CD202B, GLC3E, TIE-2, TIE2, VMCM, VMCM1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Tested Application
ELISA, WB, IHC, IF
Product Information
Product Name
anti- Tie2 antibody
Catalogue No.
FNab08690
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF) -like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Immunogen Information
Immunogen
TEK tyrosine kinase, endothelial
Synonyms
CD202B, GLC3E, TIE-2, TIE2, VMCM, VMCM1
Observed MW
126kDa
Application
Tested Application
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Uniprot information
UniProt ID
Q02763
Images
Immunohistochemistry of paraffin-embedded human lung cancer using FNab08690 (Tie2 antibody) at dilution of 1:100
mouse kidney were subjected to SDS PAGE followed by western blot with FNab08690 (Tie2 antibody) at dilution of 1:1000