Products
AK2 antibody
- Product Name
- AK2 antibody
- Catalogue No.
- FNab00244
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- adenylate kinase 2
- Alternative Names
- Adenylate kinase 2 antibody, mitochondrial (AK 2)|ATP-AMP transphosphorylase 2|ATP:AMP phosphotransferase|Adenylate monophosphate kinase|Adenylate kinase 2 antibody, mitochondrial antibody, N-terminally processed|AK2|ADK2 antibody
- UniProt ID
- P54819
- Observed MW
- 33 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab00244(AK2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab00244(AK2 antibody) at dilution of 1:100
- Background
- Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.
