Products
TCEA1 antibody
- Product Name
- TCEA1 antibody
- Catalogue No.
- FNab08545
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- transcription elongation factor A(SII), 1
- Alternative Names
- GTF2S antibody, TFIIS antibody
- UniProt ID
- P23193
- Observed MW
- 40 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
Sp2/0 cells were subjected to SDS PAGE followed by western blot with FNab08545(SII-TFIIS,TCEA1 antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human brain using FNab08545(SII-TFIIS,TCEA1 antibody) at dilution of 1:400
- Background
- Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
