Products
TBCD antibody
- Product Name
- TBCD antibody
- Catalogue No.
- FNab08519
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- tubulin folding cofactor D
- Alternative Names
- KIAA0988 antibody, SSD1 antibody, TFCD antibody
- UniProt ID
- Q9BTW9
- Observed MW
- 130 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:2000
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08519(TBCD antibody) at dilution of 1:500
IP Result of anti-TBCD (IP:FNab08519, 4ug; Detection:FNab08519 1:500) with mouse brain tissue lysate 3440ug.
- Background
- Tubulin-folding protein; involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin(TUBB). Acts as a GTPase-activating protein(GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.
