Products
SRGAP1 antibody
- Product Name
- SRGAP1 antibody
- Catalogue No.
- FNab08224
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- SLIT-ROBO Rho GTPase activating protein 1
- Alternative Names
- ARHGAP13 antibody, FLJ22166 antibody, KIAA1304 antibody, SRGAP1 antibody
- UniProt ID
- Q7Z6B7
- Observed MW
- 130 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08224(SRGAP1 antibody) at dilution of 1:800
IP Result of anti-SRGAP1 (IP:FNab08224, 4ug; Detection:FNab08224 1:500) with mouse kidney tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human testis using FNab08224(SRGAP1 antibody) at dilution of 1:50
- Background
- GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.
