mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab00282(ALDH1A1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab00282( ALDH1A1 Antibody) at dilution of 1:200
Background
The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet.