Products
SPPL2A antibody
- Product Name
- SPPL2A antibody
- Catalogue No.
- FNab08191
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- signal peptide peptidase-like 2A
- UniProt ID
- Q8TCT8
- Observed MW
- 58 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200-1:2000; IHC: 1:20-1:200
Validated Images
human colon tissue were subjected to SDS PAGE followed by western blot with FNab08191(SPPL2A antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human testis using FNab08191(SPPL2A antibody) at dilution of 1:50
- Background
- SPPL2A(Signal peptide peptidase-like 2A) is also named as IMP3(Intramembrane protease 3), PSL2(Presenilin-like protein 2) and belongs to the peptidase A22B family. It is an aspartyl intramembrane protease, has been implicated in the proteolysis of TNF-alpha, Fas Ligand and Bri2 and endogenous signal-peptide-peptidase-like2A(SPPL2a) is localised in lysosomes/late endosomes(PMID:21896273).
