Products
SNX9 antibody
- Product Name
- SNX9 antibody
- Catalogue No.
- FNab08097
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- sorting nexin 9
- Alternative Names
- SH3PX1 antibody, SH3PXD3A antibody
- UniProt ID
- Q9Y5X1
- Observed MW
- 70-78 kDa
Application
- Tested Applications
- ELISA, WB, IP, IF
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab08097(SNX9 antibody) at dilution of 1:500
IP Result of anti-SNX9 (IP:FNab08097, 3ug; Detection:FNab08097 1:1000) with mouse heart tissue lysate 9500ug.
- Background
- Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate.
