SHANK1 antibody

Catalogue No.:FNab07837Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SHANK1 antibody
Catalogue No.
FNab07837
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
SH3 and multiple ankyrin repeat domains 1
UniProt ID
Q9Y566
Observed MW
250-300 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab07837(SHANK1 antibody) at dilution of 1:300
Background
Seems to be an adapter protein in the postsynaptic density(PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.