Products
RTN3 antibody
- Product Name
- RTN3 antibody
- Catalogue No.
- FNab07523
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- reticulon 3
- Alternative Names
- ASYIP antibody, HAP antibody, NSP like protein 2 antibody, NSP like protein II antibody, NSPL2 antibody, NSPLII antibody, reticulon 3 antibody, RTN3 antibody, RTN3 A1 antibody
- UniProt ID
- O95197
- Observed MW
- 24 kDa,113 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:3000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab07523(RTN3 antibody) at dilution of 1:500
IP Result of anti-RTN3 (IP: FNab07523, 4ug; Detection: FNab07523 1:400) with HeLa cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human gliomas using FNab07523(RTN3 antibody) at dilution of 1:50
- Background
- May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. Induces the formation of endoplasmic reticulum tubules(PubMed:25612671).
