Jurkat cells were subjected to SDS PAGE followed by western blot with FNab07069(RAC2 antibody) at dilution of 1:10000
Immunohistochemistry of paraffin-embedded human spleen slide using FNab07069(RAC2 Antibody) at dilution of 1:50
Background
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species(ROS) by NADPH oxidase.